Runs are sequences of three or more successive cards of the same suit, whereas sets are groups of three or four cards of the same rank. Another optaviator india appion available to players is "laying off," which is adding cards to runs or sets that have already been placed on the table. ". . Strategies for Winning. Being aware of the cards that other players are discarding can help you win at rummy since it can reveal important details about their hand.